Acute myelogenous leukaemia (AML) is also known as acute myelocytic leukaemia, acute myeloblastic leukaemia and acute granulocytic leukaemia. It originates in the myeloid stem cells and leads to overproduction of immature non-lymphoid cells known as the blast cells. AML usually occurs above 40 years of age but it may occur in young adults and children. Myelodysplastic syndrome is considered as the major risk factor. Symptoms of acute myelogenous leukaemia include fatigue, irritability, weakness, loss of appetite, loss of weight, bone & joint pains and flu-like symptoms such as high fever, chills and respiratory discomfort. There may occur purpura, menorrhagia and bleeding from the nose, gums & the gastrointestinal tract.
There is no definite staging system for acute myelogenous leukaemia. In untreated cases of acute myelogenous leukaemia, there are too many leukaemic cells in the bone marrow and peripheral blood. In the remission stage, counts of the white blood cells in the bone marrow and the peripheral blood return to normal after the treatment. In the relapsed stage, the acute myelogenous leukaemia recurs after a remission. In the refractory stage, the acute myelogenous leukaemia fails to go into remission even after the treatment. Procedures used in the diagnosis of the acute myelogenous leukaemia include complete blood count, bone marrow biopsy and cerebrospinal fluid examination. There is no definite staging system for acute myelogenous leukaemia. In untreated cases of acute myelogenous leukaemia, there are too many leukaemic cells in the bone marrow and peripheral blood. In the remission stage, counts of the white blood cells in the bone marrow and the peripheral blood return to normal after the treatment. In the relapsed stage, the acute myelogenous leukaemia recurs after a remission. In the refractory stage, the acute myelogenous leukaemia fails to go into remission even after the treatment. Procedures used in the diagnosis of the acute myelogenous leukaemia include complete blood count, bone marrow biopsy and cerebrospinal fluid examination.
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Iris Diaz
Cancertame Private Limited
Acute Myelogenous Leukaemia (AML)