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Soft tissue sarcoma arises from the connective tissue (the tissue that supports, connects and surrounds different organs in the body) including the muscle, tendon, fat, blood vessel, nerve, fibrous tissue and the synovial tissue. Soft tissue sarcoma usually affects limbs and limb girdles. Exposure to radiation is considered as the major causative factor of the soft tissue sarcoma. Soft tissue sarcoma may develop even many years after exposure to the radiation. Chemical carcinogens (such as herbicides, pesticides and food preservatives) may also cause soft tissue sarcoma. Sometimes, neurofibromatosis transforms into the soft tissue sarcoma. It has been observed that soft tissue sarcoma grows fairly large in size by the time of diagnosis. Soft tissue sarcoma usually remains asymptomatic during early stages of the disease. The symptoms of soft tissue sarcoma vary depending on site and size of the tumour. Soft tissue sarcoma usually metastasizes to the lungs.
Staging of the soft tissue sarcoma is done as follows:
Procedures used to diagnose the soft tissue sarcoma include xerography, arteriography, ultrasound, CT scan, MRI and biopsy.
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Soft Tissue Sarcoma